Women and the risk of type 2 diabetes

Background:
High prevalence of type 2 diabetes (T2D) among minority women in Norway. Gestational diabetes (GDM) is an early marker of disturbances in the glucose metabolism, linked to T2D. We found a high prevalence of GDM in the STORK Groruddalen study (STORK-G1).

Aim:
To assess the prevalence of prediabetes and T2D (measured by HbA1c) and to explore ethnic differences in development of T2D.

Method:
11 years follow-up study of 823 pregnant women, 59% ethnic minorities (STORK-G1).

News 2022: The data collection was completed in March 2022. We have achieved a participation rate of 53% of those eligible at the 11-year follow-up with extensive clinical data collected during the Covid pandemic. Many women had moved out of the area, some were no longer living in Norway, some were not possible to reach by phone, and many women struggled with time constraints. We have dried blood spots from 94% of those who met, and fasting venous samples from 56%. A total of 85% attended the full-scale data collection. 76% of the participants used an accelerometer (Actigraph).

Publications 2022:
Waage, C. W., Mdala, I., Stigum, H., Jenum, A. K., Birkeland, K. I., Shakeel, N., ... & Sletner, L. (2022). Lipid and lipoprotein concentrations during pregnancy and associations with ethnicity. BMC Pregnancy and Childbirth, 22(1), 1-12.

Primary Investigator: Christin Waage, postdoc

Co-investigators/participants:  
Senior researchers:
Anne Karen Jenum (primary investigator), (MD; PhD/Prof)
Kåre I. Birkeland, MD; PhD/Prof)
Kåre Rønn-Richardsen (PhD)
Nilam Shakeel (MD; PhD)
Line Sletner (MD; PhD)
Nina Køpke Vøllestad (Dr. scient, Prof.)
Hilde Stendal Robinson (PhD)

Research fellows:
Karin Elisabeth Bennetter (PhD student)

External collaborators:

Active collaborators over the past year (2022): Child health clinics in Stovner and Bjerke district in Oslo

International collaborators:
Irene G.M. van Valkengoed (Prof.) at the University of Amsterdam,
Chittaranjan S. Yajnik (Prof.) (Pune, India) (primary investigator of the Pune Nutrition study).