The STORK-Groruddalen cohort study: Vitamin D and ethnic differences.

Background:
Large ethnic differences in women’s vitamin D status – but are ethnic minority women not really vitamin D deficient, despite low levels of serum vitamin D (25(OH)D)?

Aims:
Explore whether ethnic differences in vitamin D-binding protein can explain the difference in prevalence of vitamin D deficiency in a multiethnic pregnant population. Investigate if genetic variation of vitamin D-binding protein and enzymes in vitamin D metabolism can explain ethnic differences in vitamin D status measured by 25-hydroxyvitamin D.

Methods:
Population-based cohort of  pregnant women (823, 59% ethnic minorities), data collected 2008 – 2011 in gestational week  (GW) 14, 28 and 14 weeks postpartum about a range of health issues reflecting exposures and outcomes, collected by questionnaires and physical measurements. Vitamin D-binding protein and 25(OH)D from GW 14 and postpartum, and genetic variants of single nucleotide peptides from GWAS important in vitamin D metabolism will be used in statistical analysis.

News from 2020:
Low progression in the project during the Covid 19 pandemic as I work with infection control and vaccination as Chief District Medical Officer. 

Primary Investigator: Åse Ruth Eggemoen

Co-investigators/participants:  
Senior researchers:
Anne Karen Jenum, (MD; PhD/Prof)
Kåre I.Birkeland, (MD; PhD/Prof)
Gunn-Helen Moen (PhD, senior researcher)    

External collaborators: 
Leif Groop (MD, PhD/Prof), Lund University Diabetes Centre, Malmø
Ravi I. Thadhani (MD, PhD/Prof), Harvard Medical School, Boston
Camille E. Powe (MD, PhD), Massachusetts General Hospital, Boston