The Dialong Study
- the status of long-term surviors of type 1 diabetes
Long term follow up of patients with type 1 diabetes for more than 45 years. Cross-sectional study of 103 patients with type 1 diabetes and 75 control subject. Study of glycaemic burden, diabetic macrovascular and non-vascular late complications.
Methods: Coronary CT angiography, gene chip microarray analysis and Quality of Life measures, GCMS measurements of AGEs in skin
collagen, serum AGE inflammatory markers and teleomeres and GWAS, mRNA expression of fat cells, metabolomics and GWAS.
News from 2022:
- Tore Julsrud Berg has in the autumn semester been a Mary K. Iacocca Senior Visiting Research Fellow/Visiting Professor at the Joslin Diabetes Center, Harvard Medical School, Boston working with the Joslin Medalist Study in the group of Dr. George King.
- Marte Narum MD has started as a PhD student on a grant given from the Norwegian South-East Health Authority named: «Discovering success factors for surviving with type 1 diabetes for more than 50 years without coronary artery disease. The Dialong study»
Publications 2022:
Molvaer AK, Iversen MM, Igland J, Peyrot M, Tell GS, Holte KB, Monnier VM, Seljeflot I, Berg TJ. Metabolic predictors of pain, fatigue, depression and quality of life in people with long-term type 1 diabetes-the Dialong study. Diabet Med. 2023 Mar;40(3):e15009. doi: 10.1111/dme.15009. Epub 2022 Nov 29.
Aukrust SG, Holte KB, Opstad TB, Seljeflot I, Berg TJ, Helseth R NETosis in Long-Term Type 1 Diabetes Mellitus and Its Link to Coronary Artery Disease. Front Immunol. 2022 Jan 5;12:799539.