Background:
Infertility, contraceptive use and pregnancy outcomes are important health concerns for women and men with diabetes. Obesity, Type-2 diabetes and infertility is increasing in young adults, and could influence risk for cardiovascular and diabetes-related disease and offspring health. Recent Danish analyses indicate an increased risk of birth defects in the offspring of men using metformin during spermatogenesis.
Aims:
To improve understanding and treatment of reproductive health in women and men with diabetes in Norway.
Methods:
Complete analyses of interviews of women with Type-1 diabetes on family planning, sexual health and pregnancy.
Use national register data (prescriptions, births, diagnoses) to
1a) estimate rates of contraceptive use, and effect on number of pregnancies and pregnancy complications in women with diabetes.
1b) estimate rates of assisted reproductive therapy (ART), live births and pregnancy complications after ART.
2) investigate whether diabetes treatment of expecting fathers influences the risk for birth defects in the offspring.
News from 2022
- Analysis of the IVF cohort presented at poster session at the EASD meeting in Stockholm, manuscript in preparation.
- The interview project in good progress, interviews completed Feb 2023, with subsequent transcription, coding and analysis, submission of Master thesis: May 2023 for J.Anaruthan.
- Project plans: Analysis of parental use of medications and pregnancy outcomes during Spring 2023.
- Received support from the Odd Fellow Research Foundation, NOK 90 000.
Primary Investigator: Elisabeth Qvigstad, Department of Endocrinology, Oslo University Hospital
Project participants:
Cecilie Varsi, RN, PhD. Vice dean for research. Research on patient experiences using qualitative methods. Advisor of conduction and analysis of interviews.
H.L. Gulseth, MD, PhD, Research director, MD PhD., Dept. of Chronic Diseases and Ageing, Norwegian Institute of public health. Co-supervisor.
T. Lekva, post doc, MSc, PhD , Research Institute for Internal Medicine, Oslo University Hospital.
M-C.P. Roland MD, PhD, Dept of Obstetrics and Gynecology, Oslo University Hospital
S. Steintorsdottir, MD, MSc, junior consultant in the Department of Endocrinology, Oslo University Hospital.
Kristin Godang, Department of Endocrinology, Oslo University Hospital
Jesini Anurathan, RSN, Master cand Department of Endocrinology, Oslo University Hospital
Kari Furu, MScPharm, MPH, PhD, senior researcher. Center for Fertility and Health, Norwegian Institute of public health.
Siri Eldevik Haaberg MD, MPH, PhD, research director, deputy head of Center for Fertility and Health. Norwegian Institute of public health.
T. Tanbo, Professor, MD, PhD, Senior Consultant in Gynecology and Obstetrics, the Fertility center at Oslo University Hospital, Rikshospitalet.
J.R. Mellembakken MD, PhD, Senior Consultant in Gynecology and Obstetrics, the Fertility center at Oslo University Hospital, Rikshospitalet.
Line Wisting, Researcher, PhD, OUH, Division of Mental health
External collaborators:
Marjolein Memelink Iversen, Professor, PhD, RSN. Western Norway University of Applied Sciences Bergen
Ragnhild Bjarkøy Strandberg, Post doc, PhD, RSN. Western Norway University of Applied Sciences Bergen
K Berntorp, MD, PhD, Endocrinology Dept. of Endocrinology, Skåne University Hospital, Malmö, Sweden
Karin Ängeby, RSN, midwife, PhD student, Centre for Clinical Research and Education, Värmland. School of Education, Health and Social Studies, Dalaran University, Sweden
